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Year | Number of Results |
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2023 | 2 |
2024 | 2 |
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Page 1
Pembrolizumab in brain metastases of diverse histologies: phase 2 trial results.
Nat Med. 2023 Jul;29(7):1728-1737. doi: 10.1038/s41591-023-02392-7. Epub 2023 Jun 2.
Nat Med. 2023.
PMID: 37268724
Free PMC article.
Clinical Trial.
Abnormal vascular structure and function within brain metastases is linked to pembrolizumab resistance.
Kim AE, Lou KW, Giobbie-Hurder A, Chang K, Gidwani M, Hoebel K, Patel JB, Cleveland MC, Singh P, Bridge CP, Ahmed SR, Bearce BA, Liu W, Fuster-Garcia E, Lee EQ, Lin NU, Overmoyer B, Wen PY, Nayak L, Cohen JV, Dietrich J, Eichler A, Heist R, Krop I, Lawrence D, Ligibel J, Tolaney S, Mayer E, Winer E, Perrino CM, Summers EJ, Mahar M, Oh K, Shih HA, Cahill DP, Rosen BR, Yen YF, Kalpathy-Cramer J, Martinez-Lage M, Sullivan RJ, Brastianos PK, Emblem KE, Gerstner ER.
Kim AE, et al. Among authors: summers ej.
Neuro Oncol. 2024 May 3;26(5):965-974. doi: 10.1093/neuonc/noad236.
Neuro Oncol. 2024.
PMID: 38070147
Clinical Trial.
Item in Clipboard
Structural and functional vascular dysfunction within brain metastases is linked to pembrolizumab inefficacy.
Kim AE, Lou KW, Giobbie-Hurder A, Chang K, Gidwani M, Hoebel K, Patel JB, Cleveland MC, Singh P, Bridge CP, Ahmed SR, Bearce BA, Liu W, Fuster-Garcia E, Lee EQ, Lin NU, Overmoyer B, Wen PY, Nayak L, Cohen JV, Dietrich J, Eichler A, Heist R, Krop I, Lawrence D, Ligibel J, Tolaney S, Mayer E, Winer E, Perrino CM, Summers EJ, Mahar M, Oh K, Shih HA, Cahill DP, Rosen BR, Yen YF, Kalpathy-Cramer J, Martinez-Lage M, Sullivan RJ, Brastianos PK, Emblem KE, Gerstner ER.
Kim AE, et al. Among authors: summers ej.
bioRxiv [Preprint]. 2023 Aug 28:2023.08.25.554868. doi: 10.1101/2023.08.25.554868.
bioRxiv. 2023.
PMID: 37693537
Free PMC article.
Preprint.
Item in Clipboard
The ERK inhibitor LY3214996 augments anti-PD-1 immunotherapy in preclinical mouse models of BRAFV600E melanoma brain metastasis.
de Sauvage MA, Torrini C, Nieblas-Bedolla E, Summers EJ, Sullivan E, Zhang BS, Batchelor E, Marion B, Yamazawa E, Markson SC, Wakimoto H, Nayyar N, Brastianos PK.
de Sauvage MA, et al. Among authors: summers ej.
Neuro Oncol. 2024 May 3;26(5):889-901. doi: 10.1093/neuonc/noad248.
Neuro Oncol. 2024.
PMID: 38134951
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